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Sex education, appropriate for the developmental level and intellectual attainment of individuals with Down syndrome, adds to life quality by engendering healthy sexuality, reducing the risk of sexual abuse, avoiding sexual misunderstandings, preventing disease transmission, preventing unwanted pregnancy and alleviating other problems related to sexual function. In the past, sexuality was not considered an issue for any people with Down syndrome because of the inaccurate belief that intellectual disability formerly known as mental retardation produced permanent childhood. In fact, all people with Down syndrome have sexual feelings and intimacy needs. It is important that expression of these feelings in socially acceptable, age appropriate ways be recognized by families and caregivers.
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Turner Syndrome

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Turner Syndrome (Monosomy X) in Children | Cedars-Sinai

Initially, Rett syndrome was recognized only in females. It was hypothesized that Rett syndrome was lethal in males. This suggested that Rett syndrome was a sex-linked genetic disorder with the gene being localized on the X chromosome. The clinical features of Rett syndrome were first described in by Dr. Andreas Rett.
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Males with MECP2 Mutations

Turner syndrome TS is a genetic condition found in females only. It affects about 1 in every 2, girls. Girls with Turner syndrome are usually shorter than their peers. The good news is that if TS is diagnosed while a girl is still growing, she can be treated with growth hormones to help her grow taller.
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Turner syndrome, a condition that affects only females, results when one of the X chromosomes sex chromosomes is missing or partially missing. Turner syndrome can cause a variety of medical and developmental problems, including short height, failure of the ovaries to develop and heart defects. Turner syndrome may be diagnosed before birth prenatally , during infancy or in early childhood. Occasionally, in females with mild signs and symptoms of Turner syndrome, the diagnosis is delayed until the teen or young adult years. Girls and women with Turner syndrome need ongoing medical care from a variety of specialists.
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